SIM4NEXUS is MAGIC-NEXUS H2020 Synergy Partner. Water, land, food, energy, and climate are interconnected, comprising a coherent system (the ‘Nexus’), dominated by complexity and feedback. Putting pressure on one part of the Nexus can create pressures on the others. Management of the Nexus is critical to securing the efficient use of our scarce resources. Through the five nexus themes, SIM4NEXUS aims to predict society-wide impacts of resource use and relevant policies on sectors such as agriculture, water, biodiversity and ecosystem services through a model-based analysis.